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Temporal Representations of Odors in an Olfactory Network

Laurent, Gilles and Wehr, Michael and Davidowitz, Hananel (1996) Temporal Representations of Odors in an Olfactory Network. Journal of Neuroscience, 16 (12). pp. 3837-3847. ISSN 0270-6474. PMCID PMC6578619. https://resolver.caltech.edu/CaltechAUTHORS:20191101-092041096

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Abstract

The responses of projection neurons in the antennal lobe of the locust brain (the functional analog of mitral–tufted cells in the vertebrate olfactory bulb) to natural blends and simple odors were studied with multiple intra- and extracellular recordings in vivo. Individual odors evoked complex temporal response patterns in many neurons. These patterns differed across odors for a given neuron and across neurons for a given odor, but were stable for each neuron over repeated presentations (separated by seconds to minutes) of the same odor. The response of individual neurons to an odor was superimposed on an odor-specific coherent oscillatory population activity. Each neuron usually participated in the coherent oscillations during one or more specific epochs of the ensemble activity. These epochs of phase locking were reliable for each neuron over tens of repeated presentations of one odor. The timing of these epochs of synchronization differed across neurons and odors. Correlated activity of specific pairs of neurons, hence, generally occurred transiently during the population response, at times that were specific to these pairs and to the odor smelled. The field potential oscillations, therefore, fail to reveal a progressive transformation of the synchronized ensemble as the response to the odor unfolds. We propose that (1) odors are represented by spatially andtemporally distributed ensembles of coherently firing neurons, and (2) the field potential oscillations that characterize odor responses in the olfactory system occur, at least in this animal, in parallel with a slower dynamic odor representation.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1523/jneurosci.16-12-03837.1996DOIArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6578619PubMed CentralArticle
ORCID:
AuthorORCID
Laurent, Gilles0000-0002-2296-114X
Additional Information:© 1996 Society for Neuroscience. Received Dec. 7, 1995; revised Feb. 23, 1996; accepted April 3, 1996. This work was supported by an Office of Naval Research graduate student fellowship to M.W., and a National Science Foundation (NSF) grant and an NSF Presidential Faculty Fellow award to G.L.
Funders:
Funding AgencyGrant Number
Office of Naval Research (ONR)UNSPECIFIED
NSFUNSPECIFIED
Subject Keywords:locust; olfaction; coding; cross-correlation; synchronization; oscillation
Issue or Number:12
PubMed Central ID:PMC6578619
Record Number:CaltechAUTHORS:20191101-092041096
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20191101-092041096
Official Citation:Temporal Representations of Odors in an Olfactory Network. Gilles Laurent, Michael Wehr, Hananel Davidowitz. Journal of Neuroscience 15 June 1996, 16 (12) 3837-3847; DOI: 10.1523/JNEUROSCI.16-12-03837.1996
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:99612
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:01 Nov 2019 16:33
Last Modified:01 Nov 2019 16:33

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