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A Microfabricated Rotary Pump

Chou, Hou-Pu and Unger, Marc A. and Quake, Stephen R. (2001) A Microfabricated Rotary Pump. Biomedical Microdevices, 3 (4). pp. 323-330. ISSN 1387-2176. doi:10.1023/a:1012412916446.

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Because microfluidic devices operate at low Reynolds number, many fluidic operations are limited by diffusion. We have developed a microfabricated rotary pump and demonstrated that active mixing can be used to overcome the slow diffusion process in two applications. First, we showed that mixing of reagents could be efficiently accomplished for objects of a wide range of diffusion constants. Second, we showed how reaction kinetics of a surface-binding assay can be enhanced by nearly two orders of magnitude.

Item Type:Article
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Additional Information:© 2001 Kluwer Academic Publishers. This work was partially supported by the NIH HG 01642-04. We thank J.P. Brody and A. Groisman for helpful discussions.
Funding AgencyGrant Number
NIHHG 01642-04
Subject Keywords:microfluidics; microelectromechanical systems; soft lithography; lab on a chip; diffusion
Issue or Number:4
Record Number:CaltechAUTHORS:20191106-160557938
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Official Citation:Chou, HP., Unger, M.A. & Quake, S.R. Biomedical Microdevices (2001) 3: 323.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:99715
Deposited By: Tony Diaz
Deposited On:07 Nov 2019 00:19
Last Modified:16 Nov 2021 17:48

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