of 3
Supplementary Materials for
Functional ultrasound imaging of human brain activity through an
acoustically transparent cranial window
Claire Rabut
et al.
Corresponding author: Sumner L. Norman, sumnern@caltech.edu; Charles Liu, cliu@usc.edu;
Richard A. Andersen, richard.andersen@vis.caltech.edu; Mikhail G. Shapiro, mikhail@caltech.edu
Sci. Transl. Med.
16
, eadj3143 (2024)
DOI: 10.1126/scitranslmed.adj3143
The PDF file includes:
Figs. S1 and S2
Legend for data file S1
References (
54
)
Other Supplementary Material for this manuscript includes the following:
Data file S1
MDAR Reproducibility Checklist
Submitted Manuscript: Confidential
Template revised November 2022
Supplementary Materials
Fig. S1: Common functional brain activity recording modalities.
(
A
)
Chart comparing the
spatial
resolution, coverage, and ability to record moving subjects
of functional brain activity recording methods.
(B)
Example experimental setups for recording in humans using fMRI or electrical recording implants
(Adapted with permission from (
54
)).
Submitted Manuscript: Confidential
Template revised November 2022
Fig. S2: In vivo characterization of PMMA as a sonolucent implant for fUSI
.
(
A
) For each
condition (implant material, thickness) two ROIs
are analyzed: the cortex (i) and subcortical
structures
(ii)
. Scale, 5mm.
(
B
) Enlarged fUSI image of
Fig
. 2H
for clear localization of region
used to calculate mean fUSI over time in rat brain. (
C
) For regions
i. and ii. in panel
A
, the local
maxima (red stars) and local minima (blue stars) are calculated along each depth to determine the
signal to noise ratio.