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Published September 16, 2016 | Published
Journal Article Open

Enantioconvergent catalysis


An enantioconvergent catalytic process has the potential to convert a racemic starting material to a single highly enantioenriched product with a maximum yield of 100%. Three mechanistically distinct approaches to effecting enantioconvergent catalysis are identified, and recent examples of each are highlighted. These processes are compared to related, non-enantioconvergent methods.

Additional Information

© 2016 Mohr et al.; licensee Beilstein-Institut. This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (http://www.beilstein-journals.org/bjoc) Received: 29 July 2016. Accepted: 25 August 2016. Published: 16 September 2016. This article is part of the Thematic Series "Strategies in asymmetric catalysis". Guest Editor: T. P. Yoon. This publication is supported in part by the NIH-NIGMS (R01GM080269), Amgen, Eli Lilly (predoctoral fellowship to J. Mohr), and NIH 1F32 (GM116304-01) (postdoctoral fellowship to J. Moore). Additionally, we thank David C. Ebner for helpful discussions.

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