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Published June 2017 | public
Book Section - Chapter

Implantable phototherapy device to treat diabetic retinopathy


This paper reports on the first implantable phototherapy device to treat diabetic retinopathy by modulating rod cell metabolism through reduction of dark current. Utilizing a tritium-based radioluminescent light source capable of emitting around 505nm, the device achieves phototherapeutic activity for up to a 12-year service lifetime and <30mm^3 size. The unique scleral anchoring system facilitates simple, rapid, and robust implantation into the eye. Implantation into a rabbit model demonstrated safety over a 4-week period with no adverse effects observed.

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© 2017 IEEE. Thanks to the Caltech MEMS Lab members for their guidance with techniques and fabrication. Graduate scholarship provided by Natural Sciences and Engineering Research Council of Canada.

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October 18, 2023