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Published May 17, 2011 | Published
Book Section - Chapter Open

Field-based multiplex and quantitative assay platforms for diagnostics


The U.S. military has a continued interest in the development of handheld, field-usable sensors and test kits for a variety of diagnostic applications, such as traumatic brain injury (TBI) and infectious diseases. Field-use presents unique challenges for biosensor design, both for the readout unit and for the biological assay platform. We have developed robust biosensor devices that offer ultra-high sensitivity and also meet field-use needs. The systems under development include a multiplexed quantitative lateral flow test strip for TBI diagnostics, a field test kit for the diagnosis of pathogens endemic to the Middle East, and a microfluidic assay platform with a label-free reader for performing complex biological automated assays in the field.

Additional Information

© 2011 SPIE. This work was funded by support from an Army SBIR contract (Contract # W81XWH07-C-0031) and an Air Force SBIR Contract (FA8650-07-C-6757). The author is indebted to project technical monitors Dr. Madhusoodana Nambiar and Dr. Camilla Mauzy for their suggestions and support in the development of this work.

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