Published February 2006 | Version public
Journal Article

Digital genetics: unravelling the genetic basis of evolution

Abstract

Digital genetics, or the genetics of digital organisms, is a new field of research that has become possible as a result of the remarkable power of evolution experiments that use computers. Self-replicating strands of computer code that inhabit specially prepared computers can mutate, evolve and adapt to their environment. Digital organisms make it easy to conduct repeatable, controlled experiments, which have a perfect genetic 'fossil record'. This allows researchers to address fundamental questions about the genetic basis of the evolution of complexity, genome organization, robustness and evolvability, and to test the consequences of mutations, including their interaction and recombination, on the fate of populations and lineages.

Additional Information

© 2006 Nature Publishing Group. I would like to thank R.E. Lenski, D. Misevic, C. Ofria, and C.O. Wilke for extensive discussions. I am further indebted to D. Misevic for kindly providing me with figure 1b, and D. Weise for the illustration in box 3.

Additional details

Identifiers

Eprint ID
55898
DOI
10.1038/nrg1771
Resolver ID
CaltechAUTHORS:20150318-140720858

Related works

Describes
10.1038/nrg1771 (DOI)

Dates

Created
2015-03-18
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Updated
2021-11-10
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