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Published August 20, 2012 | Published
Journal Article Open

Digital optical phase conjugation of fluorescence in turbid tissue

Abstract

We demonstrate a method for phase conjugating fluorescence. Our method, called reference free digital optical phase conjugation, can conjugate extremely weak, incoherent optical signals. It was used to phase conjugate fluorescent light originating from a bead covered with 0.5 mm of light-scattering tissue. The phase conjugated beam refocuses onto the bead and causes a local increase of over two orders of magnitude in the light intensity. Potential applications are in imaging, optical trapping, and targeted photochemical activation inside turbid tissue.

Additional Information

© 2012 American Institute of Physics. Received 25 February 2012; accepted 30 July 2012; published online 22 August 2012. This work was funded by NIH under Grant No. 1DP2OD007307-01.

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Published - ApplPhysLett_101_081108.pdf

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