Published May 14, 2021 | Version Accepted Version
Journal Article Open

Investigate the origins of COVID-19

  • 1. ROR icon Fred Hutchinson Cancer Research Center
  • 2. ROR icon Howard Hughes Medical Institute
  • 3. ROR icon Broad Institute
  • 4. ROR icon University of North Carolina at Chapel Hill
  • 5. ROR icon California Institute of Technology
  • 6. ROR icon University of Chicago
  • 7. ROR icon University of Toronto
  • 8. ROR icon University of Cambridge
  • 9. ROR icon Yale University
  • 10. ROR icon Harvard University
  • 11. ROR icon University of Basel
  • 12. ROR icon University of California, Berkeley
  • 13. ROR icon Stanford University
  • 14. ROR icon University of Arizona

Abstract

On 30 December 2019, the Program for Monitoring Emerging Diseases notified the world about a pneumonia of unknown cause in Wuhan, China (1). Since then, scientists have made remarkable progress in understanding the causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), its transmission, pathogenesis, and mitigation by vaccines, therapeutics, and non-pharmaceutical interventions. Yet more investigation is still needed to determine the origin of the pandemic. Theories of accidental release from a lab and zoonotic spillover both remain viable. Knowing how COVID-19 emerged is critical for informing global strategies to mitigate the risk of future outbreaks.

Additional Information

© 2021 American Association for the Advancement of Science. This is an article distributed under the terms of the Science Journals Default License.

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Accepted Version - nihms-1834584.pdf

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Additional details

Identifiers

PMCID
PMC9520851
Eprint ID
109115
Resolver ID
CaltechAUTHORS:20210513-115757419

Dates

Created
2021-05-13
Created from EPrint's datestamp field
Updated
2023-07-07
Created from EPrint's last_modified field

Caltech Custom Metadata

Caltech groups
COVID-19, Division of Biology and Biological Engineering (BBE)