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Published November 10, 2017 | Published
Journal Article Open

Correspondence: Reply to 'Revisiting the theoretical cell membrane thermal capacitance response'


We thank Plaksin, Kimmel, and Shoham for their correspondence regarding our 2012 article on the mechanism of infrared stimulation of excitable cells. In this study, we showed that the heating of cellular water by infrared light leads to an increase in the electrical capacitance of the cell membrane. This time-varying capacitance produces a current leading to membrane depolarization and generation of action potentials. Although our experimental findings were the primary focus of the paper and account for most of its impact to date, we also attempted to provide a theoretical explanation of how the membrane capacitance changes with temperature.

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© 2017 The Authors. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. Received: 22 March 2017; Accepted: 28 June 2017; Published online 10 November 2017. Author Contributions: All authors contributed to writing this Correspondence and agree with its contents. The authors declare no competing financial interests.

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August 19, 2023
August 19, 2023