Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published August 15, 1968 | Published
Journal Article Open

A Proton Magnetic Resonance Study of The Interaction of Adenosine with Polyuridylic Acid: Evidence for Both Adenine-Uracil Base-Stacking and Base-Pairing


We report here a proton magnetic resonance (pmr) study of the interaction of adenosine with polyuridylic acid in aqueous solution. The results of this study indicate that the mode of interaction is adenosine intercalation and adenine-uracil base-stacking above 26[degrees]C, and verifies that a triple-stranded complex which is stabilized by both adenine-uracil hydrogen-bonding and adenine-adenine base-stacking is formed below this temperature. Some information regarding the dynamics of these processes has also been obtained.

Additional Information

© 1968 by the National Academy of Sciences Communicated by Norman Davidson, May 15, 1968 This work was supported in part by grant GM-14523-02, U.S. Public Health Service. Noyes Laboratory of Chemical Physics, Contribution no. 3676.

Attached Files

Published - BANpnas68.pdf


Files (806.4 kB)
Name Size Download all
806.4 kB Preview Download

Additional details

August 21, 2023
October 23, 2023