Coding for Optimized Writing Rate in DNA Storage
A method for encoding information in DNA sequences is described. The method is based on the precision-resolution framework, and is aimed to work in conjunction with a recently suggested terminator-free template independent DNA synthesis method. The suggested method optimizes the amount of information bits per synthesis time unit, namely, the writing rate. Additionally, the encoding scheme studied here takes into account the existence of multiple copies of the DNA sequence, which are independently distorted. Finally, quantizers for various run-length distributions are designed.
This work was supported in part by a United States–Israel Binational Science Foundation (BSF) under grant no. 2017652, and by NSF grants under grant nos. CCF-1816409, CCF-1755773, CCF-1816965, and CCF-1717884.
Submitted - etr148.pdf