Published October 2003
| public
Journal Article
Diverse roles for ubiquitin-dependent proteolysis in transcriptional activation
- Creators
- Lipford, J. Russell
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Deshaies, Raymond J.
Abstract
A growing literature points to a fundamental role for the ubiquitin–proteasome degradation system (UPS) in transcription. Four recent publications add significant insight to our understanding of the connections between these processes. Each provides evidence that some aspect of the UPS can stimulate the activity of transcriptional activators. UPS might promote transcription by several mechanisms, and in some cases, even the final step of the UPS — proteolysis — might enhance activator function.
Additional Information
© 2003 Nature Publishing Group.Additional details
- Eprint ID
- 56217
- Resolver ID
- CaltechAUTHORS:20150330-125857288
- Created
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2015-03-31Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field