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Published March 2010 | Published
Journal Article Open

Compressed sensing in photoacoustic tomography in vivo


The data acquisition speed in photoacoustic computed tomography (PACT) is limited by the laser repetition rate and the number of parallel ultrasound detecting channels. Reconstructing an image with fewer measurements can effectively accelerate the data acquisition and reduce the system cost. We adapt compressed sensing (CS) for the reconstruction in PACT. CS-based PACT is implemented as a nonlinear conjugate gradient descent algorithm and tested with both phantom and in vivo experiments.

Additional Information

© 2010 SPIE. Paper 09353SSRR received Aug. 11, 2009; revised manuscript received Feb. 11, 2010; accepted for publication Feb. 11, 2010; published online Apr. 12, 2010. This work was sponsored in part by National Institutes of Health Grant Nos. R01 EB008085, U54 CA136398, R01 CA113453901, R01 NS46214 (BRP), and R01 EB000712. L.W. has a financial interest in Microphotoacoustic, Inc., and Endra, Inc., which, however, did not support this work.

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