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Published February 24, 2009 | Published
Book Section - Chapter Open

The speckle-free nature of photoacoustic imaging


Photoacoustic imaging for biomedical applications has seen significant growth during the past few years. Despite its coherent nature, it possesses a unique advantage to produce images devoid of speckle artifacts. The reason responsible for this salient feature has not been addressed so far. We found this is a direct result of its extraordinary absorption contrast. Our discovery is explained using simulations based on a practical photoacoustic imaging system.

Additional Information

© 2009 Society of Photo-Optical Instrumentation Engineers (SPIE). We would like to thank Meng-Lin Li, Minghua Xu and Roger Zemp for useful discussion. This research is funded in part by the National Institutes of Health under Grant No. R01 NS46214 (BRP) and R01 EB000712.

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