Supramolecular guests in solvent driven block copolymer assembly: from internally structured nanoparticles to micelles
Supramolecular interactions between different hydrogen-bonding guests and poly(2-vinylpyridine)-block-poly(styrene) can be exploited to prepare remarkably diverse self-assembled nanostructures in dispersion from a single block copolymer (BCP). The characteristics of the BCP can be efficiently controlled by tailoring the properties of a guest which preferentially binds to the P2VP block. For example, the incorporation of a hydrophobic guest creates a hydrophobic BCP complex that forms phase separated nanoparticles upon self-assembly. Conversely, the incorporation of a hydrophilic guest results in an amphiphilic BCP complex that forms spherical micelles in water. The ability to tune the self-assembly behavior and access dramatically different nanostructures from a single BCP substrate demonstrates the exceptional versatility of the self-assembly of BCPs driven by supramolecular interactions. This approach represents a new methodology that will enable the further design of complex, responsive self-assembled nanostructures.
Additional Information© 2013 The Royal Society of Chemistry. Received 8th June 2013 , Accepted 1st July 2013. First published on 5th July 2013. Funding from an Australian Research Council International Fellowship (LAC), Australian American Association Sir Keith Murdoch Fellowship (LAC), and the DOE Office of Science Graduate Fellowship Program (MJR) is gratefully acknowledged. This work was also supported by the MRSEC Program of the National Science Foundation under Award DMR-0520415 and DMR-1121053 and in part with Federal funds from the National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, under Contract no. HHSN268201000046C.
Accepted Version - nihms502309.pdf
Supplemental Material - c3py00750b.pdf