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Published July 2002 | Published
Journal Article Open

Time-domain reconstruction for thermoacoustic tomography in a spherical geometry


Reconstruction-based microwave-induced thermoacoustic tomography in a spherical configuration is presented. Thermoacoustic waves from biological tissue samples excited by microwave pulses are measured by a wide-band unfocused ultrasonic transducer, which is set on a spherical surface enclosing the sample. Sufficient data are acquired from different directions to reconstruct the microwave absorption distribution. An exact reconstruction solution is derived and approximated to a modified backprojection algorithm. Experiments demonstrate that the reconstructed images agree well with the original samples. The spatial resolution of the system reaches 0.5 mm.

Additional Information

© 2002 IEEE. Manuscript received May 15, 2001; revised May 13, 2002. This work was supported in part by the U.S. Army under Medical Research and Material Command under Grant DAMD17-00-1-0455, in part by the National Institutes of Health (NIH) under Grant R01 CA71980, in part by the National Science Foundation (NSF) under Grant BES-9734491, and in part by the Texas Higher Education Coordinating Board under Grant ARP 000512-0123-1999.

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August 19, 2023
October 19, 2023