High-NA-based virtual point detectors for photoacoustic imaging
We demonstrated the focal point of a high-numerical-aperture (NA) ultrasonic transducer can be used as a virtual point detector. This virtual point detector detects omnidirectionally over a wide acceptance angle. It also combines a large active transducer surface and a small effective virtual detector size, thus the sensitivity is high compared with that of a real point detector, and the aperture effect is small compared with that of a finite size transducer. Phantom experiments are provided to demonstrate the applications of high-NA-based virtual point detectors in photoacoustic tomography and thermoacoustic tomography. The virtual point detector is also used to image the cerebral cortex of mice.
Additional Information© 2009 Society of Photo-Optical Instrumentation Engineers (SPIE). This project was sponsored in part by National Institutes of Health Grant Nos. R01 EB000712, R01 NS46214(BRP), R01 EB000712, and U54 CA136398. L. Wang has a financial interest in Endra, Inc., which, however, did not support this work.
Published - 71770R.pdf