Speckle in photoacoustic tomography
Photoacoustic tomography is emerging as a promising imaging modality for various biomedical applications. Unlike traditional ultrasound imaging that is plagued by strong speckle artifacts, no obvious speckle has so far been observed in photoacoustic images. We systematically studied the reason for this lack of speckle in photoacoustic tomography based on speckle contrast. Theoretical explanations were validated by simulation. The results here can serve as a basis for developing specific applications, such as tissue characterization, using photoacoustic methods.
Additional Information© 2006 Society of Photo-Optical Instrumentation Engineers (SPIE). This project is sponsored by the National Institutes of Health grants R01 NS46214 and R01 EB000712.
Published - 60860Y.pdf