Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published July 20, 2011 | public
Journal Article

4D Scanning Transmission Ultrafast Electron Microscopy: Single-Particle Imaging and Spectroscopy


We report the development of 4D scanning transmission ultrafast electron microscopy (ST-UEM). The method was demonstrated in the imaging of silver nanowires and gold nanoparticles. For the wire, the mechanical motion and shape morphological dynamics were imaged, and from the images we obtained the resonance frequency and the dephasing time of the motion. Moreover, we demonstrate here the simultaneous acquisition of dark-field images and electron energy loss spectra from a single gold nanoparticle, which is not possible with conventional methods. The local probing capabilities of ST-UEM open new avenues for probing dynamic processes, from single isolated to embedded nanostructures, without being affected by the heterogeneous processes of ensemble-averaged dynamics. Such methodology promises to have wide-ranging applications in materials science and in single-particle biological imaging.

Additional Information

© 2011 American Chemical Society. Received: April 26, 2011. Publication Date (Web): May 26, 2011. A.H.Z. acknowledges the helpful discussion with Prof. Archie Howie regarding STEM. This work was supported by National Science Foundation Grant DMR-0964886 and Air Force Office of Scientific Research Grant FA9550-07-1-0484 in Caltech's Physical Biology Center for Ultrafast Science and Technology, supported by the Gordon and Betty Moore Foundation.

Additional details

August 19, 2023
October 24, 2023