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Published May 19, 1994 | Published
Book Section - Chapter Open

Detection of an object inside a phantom tissue using a spatial filter


We report the detection of an object inside a phantom tissue using a spatial filter and a 5-mW He-Ne Laser. The phantom tissue is composed of 8% scattering polystyrene spheres and is diluted to different concentrations in water. The solution is placed inside of a cuvette of length 5 cm and width 5 cm. The spatial filter, composed of a 4-cm plano-convex lens and a 10-micrometers pinhole, is able to extract ballistic and quasi-ballistic photons from the transmitted light. A photomultiplier tube is used for detection, and a lock-in amplifier is used to reduce the amount of noise in the signal. We are able to detect the object in a phantom tissue of 20 mean free paths [mfp] with a contrast of 99.0%. The contrast in a tissue with 30 mfp is 22.7%.

Additional Information

© 1994 Society of Photo-Optical Instrumentation Engineers (SPIE). This research was performed as a summer internship cooperative between Rice University and UT MD Anderson Cancer Center in Houston, Texas. The author wishes to thank the Center for Theoretical Study of Physical Systems at Clark Atlanta University, the Rice Quantum Institute, and the Spend a Summer with a Scientist Program at Rice University for their financial contributions.

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August 20, 2023
August 20, 2023