Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published February 28, 2008 | Published
Book Section - Chapter Open

Photoacoustic tomography with novel optical contrast agents based on gold nanocages or nanoparticles containing near-infrared dyes


Poly(ethylene glycol)-coated Au nanocages have been evaluated as a potential near-infrared (NIR) contrast agent for photoacoustic tomography (PAT). Previously, Au nanoshells were found to be an effective NIR contrast agent for PAT; however, Au nanocages, with their more compact sizes (<50 nm compared to >100 nm for Au nanoshells) and larger optical absorption cross-sections, should be better suited for in vivo applications. In this study, we tested Au nanocages as a contrast agent for PAT. The result suggests that Au nanocages are promising contrast agents for our applications. We also present PAT results when novel, dye-containing nanoparticles are used as contrast agents.

Additional Information

© 2008 Society of Photo-Optical Instrumentation Engineers (SPIE). This project was sponsored in part by National Institutes of Health Grant Nos. R01 CA106728 and R01 NS46214 (BRP) as well as a Director's Pioneer Award (5DP1OD000798 to Y. X.) and a grant from NSF (DMR-0451788 to Y. X.). Part of this work was performed at the UW Nanotech User Facility (NTUF), a member of the National Nanotechnology Infrastructure Network (NNIN) funded by NSF.

Attached Files

Published - 68560I.pdf


Files (422.6 kB)
Name Size Download all
422.6 kB Preview Download

Additional details

August 19, 2023
January 14, 2024