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Published July 1, 2003 | Published
Book Section - Chapter Open

Effects of acoustic heterogeneity on the breast thermoacoustic tomography


The effects of wavefront distortions induced by acoustic heterogeneities in breast thermoacoustic tomography (TAT) are studied. First, amplitude distortions are shown to be insignificant for different scales of acoustic heterogeneities. Next, the effects of phase distortions (errors in time-of-flight) in our numerical studies are investigated, and the spreads of point sources and boundaries caused by the phase distortions are studied. After that, a demonstration showing that the blurring of images can be compensated for by using the distribution of acoustic velocity in the tissues in the reconstructions is presented. Last, the differences in the effects of acoustic heterogeneity and the generation of speckles in breast TAT and breast ultrasound imaging are discussed.

Additional Information

© 2003 Society of Photo-Optical Instrumentation Engineers (SPIE). We would like to thank Dr. Q. Zhu for many useful discussions. This project was sponsored in part by the U.S. Army Medical Research and Materiel Command Grant No. DAMD17-00-1-0455, the National Institutes of Health Grants No. R01 CA71980 and No. R21 CA83760, the National Science Foundation Grant No. BES-9734491, and Texas Higher Education Coordinating Board Grant No. ARP 000512-0063-2001.

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