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Published September 2009 | Published
Journal Article Open

Thermoacoustic and photoacoustic sensing of temperature

Abstract

We present a novel temperature-sensing technique using thermoacoustic and photoacoustic measurements. This noninvasive method has been demonstrated using a tissue phantom to have high temporal resolution and temperature sensitivity. Because both photoacoustic and thermoacoustic signal amplitudes depend on the temperature of the source object, the signal amplitudes can be used to monitor the temperature. A temperature sensitivity of 0.15°C was obtained at a temporal resolution as short as 2s, taking the average of 20 signals. The deep-tissue imaging capability of this technique can potentially lead us to in vivo temperature monitoring in thermal or cryogenic applications.

Additional Information

© 2009 SPIE. Paper 09158R received Apr. 23, 2009; revised manuscript received Jul. 7, 2009; accepted for publication Aug. 6, 2009; published online Oct. 12, 2009. This work was sponsored by National Institutes of Health Grants No. R01 EB000712, No. R01 NS46214 (Bioengineering Research Partnerships), No. R01 EB008085, and No. U54 CA136398 (Network for Translational Research). L.W. has a financial interest in Endra, Inc., which, however, did not support this work. We thank Claire Cobley for her help with the spectrophotometer and James Ballard for helping us with the manuscript preparation.

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August 21, 2023
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