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Published April 15, 1999 | Published
Journal Article Open

Two-dimensional depth-resolved Mueller matrix characterization of biological tissue by optical coherence tomography


We built a polarization-sensitive optical coherence tomographic system and measured the two-dimensional depth-resolved full 4×4 Mueller matrix of biological tissue for what is believed to be the first time. The Mueller matrix measurements, which we made by varying the polarization states of the light source and the detector, yielded a complete characterization of the polarization property of the tissue sample. The initial experimental results indicated that this new approach reveals some tissue structures that are not perceptible in standard optical coherence tomography.

Additional Information

© 1999 Optical Society of America. Received December 15, 1998. Thanks to C. B. Su for experimental assistance. This study was sponsored in part by National Institutes of Health grants R29 CA68562 and R01 CA71980 and by National Science Foundation grant BES-9734491.

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