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Published April 2014 | Accepted Version
Journal Article Open

Breakthroughs in Photonics 2013: Photoacoustic Tomography in Biomedicine


Photoacoustic tomography (PAT) is one of the fastest growing biomedical imaging modalities in the last decade. Building on its high scalability and complementary imaging contrast to other mainstream modalities, PAT has gained substantial momentum in both preclinical and clinical studies. In 2013, PAT has grown markedly in both its technological capabilities and biomedical applications. In particular, breakthroughs have been made in super-resolution imaging, deep blood flow measurement, small animal resting state brain mapping, video rate functional human imaging, and human breast imaging. These breakthroughs have either successfully solved long-standing technical issues in PAT or significantly enhanced its imaging capability. This review will summarize state-of-the-art developments in PAT and highlight a few representative achievements of the year 2013.

Additional Information

© 2014 IEEE. Manuscript received February 13, 2014; revised February 26, 2014; accepted March 1, 2014. Date of publication March 11, 2014; date of current version April 30, 2014. This work was sponsored by NIH Grants DP1 EB016986 (NIH Director's Pioneer Award), R01 CA186567 (NIH Director's Transformative Research Award), R01 EB016963, R01 CA134539, R01 EB010049, R01 CA157277, and R01 CA159959. The authors appreciate Prof. J. Ballard's close reading of the manuscript. L. V. Wang has a financial interest in Endra, Inc., and Microphotoacoustics, Inc., which, however, did not support this work.

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Accepted Version - nihms573800.pdf


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