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Published November 2003 | metadata_only
Journal Article

Crystal gazing in optical microscopy


For most of the three centuries after Hooke introduced optical microscopy, refinement of the instrumentation and approach made microscopes more convenient than anything else. A modern reader of Hooke's classic treatise Micrographia (ca. 1655) has no problem in visualizing the instrument employed; as in modern microscopes, a light source, an objective lens and an eyepiece were used to project an image magnified a 100-fold to a 1,000-fold into a human eye. This range of magnifications and resolution (~200 nm) has brought cellular morphology and tissue structure into view and made optical microscopy the perfect partner for biological investigation.

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© 2003 Nature Publishing Group.

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August 19, 2023
August 19, 2023