Published January 21, 2022 | Version Supplemental Material + Published
Journal Article Open

Reinforcement learning reveals fundamental limits on the mixing of active particles

  • 1. ROR icon California Institute of Technology
  • 2. ROR icon Carnegie Mellon University

Abstract

The control of far-from-equilibrium physical systems, including active materials, requires advanced control strategies due to the non-linear dynamics and long-range interactions between particles, preventing explicit solutions to optimal control problems. In such situations, Reinforcement Learning (RL) has emerged as an approach to derive suitable control strategies. However, for active matter systems, it is an important open question how the mathematical structure and the physical properties determine the tractability of RL. In this paper, we demonstrate that RL can only find good mixing strategies for active matter systems that combine attractive and repulsive interactions. Using analytic results from dynamical systems theory, we show that combining both interaction types is indeed necessary for the existence of mixing-inducing hyperbolic dynamics and therefore the ability of RL to find homogeneous mixing strategies. In particular, we show that for drag-dominated translational-invariant particle systems, mixing relies on combined attractive and repulsive interactions. Therefore, our work demonstrates which experimental developments need to be made to make protein-based active matter applicable, and it provides some classification of microscopic interactions based on macroscopic behavior.

Additional Information

© The Royal Society of Chemistry 2022. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Submitted 29 Sep 2021; Accepted 11 Dec 2021; First published 13 Dec 2021. We thank Arjuna Subramanian, Jerry Wang, Pranav Bhamidipati, Ivan Jimenez, Jeremy Bernstein, Dr Guannan Qu, Dr Christopher Miles, and Dr Shahriar Shadkhoo for scientific discussions and feedback on the manuscript. We thank Inna-Marie Strazhnik for help with the figures. We acknowledge funding through the Foundational Questions Institute and Fetzer Franklin Fund through FQXi 1816, the Packard Foundation (2019-69662), and the Heritage medical research institute. ANP acknowledges additional funding through the SFP SURF program. Author contributions. DS and MT conceived the project. DS, ANP, and JS wrote the simulation environment. DS performed the simulations and analyzed the results. DS and MT wrote the manuscript with input from all authors. There are no conflicts to declare.

Attached Files

Published - d1sm01400e.pdf

Supplemental Material - d1sm01400e1.pdf

Files

d1sm01400e.pdf

Files (8.4 MB)

Name Size Download all
md5:f5898a7e3b04ae8b28124ff2a78e13a1
3.4 MB Preview Download
md5:6e6d3adc8288cf860c62c629da80ea98
5.0 MB Preview Download

Additional details

Identifiers

Eprint ID
112615
Resolver ID
CaltechAUTHORS:20211221-866382000

Related works

Describes
10.1039/D1SM01400E (DOI)

Funding

Foundational Questions Institute (FQXI)
1816
David and Lucile Packard Foundation
2019-69662
Heritage Medical Research Institute
Caltech Summer Undergraduate Research Fellowship (SURF)

Dates

Created
2021-12-21
Created from EPrint's datestamp field
Updated
2022-01-24
Created from EPrint's last_modified field

Caltech Custom Metadata

Caltech groups
Heritage Medical Research Institute, Division of Biology and Biological Engineering (BBE)