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Published March 2016 | Supplemental Material
Journal Article Open

Cuffing-based photoacoustic flowmetry in humans in the optical diffusive regime


Measuring blood flow speed in the optical diffusive regime in humans has been a long standing challenge for photoacoustic tomography. In this work, we proposed a cuffing-based method to quantify blood flow speed in humans with a handheld photoacoustic probe. By cuffing and releasing the blood vessel, we can measure the blood flow speed downstream. In phantom experiments, we demonstrated that the minimum and maximum measurable flow speeds were 0.035 mm/s and 42 mm/s, respectively. In human experiments, flow speeds were measured in three different blood vessels: a radial artery in the right forearm, a radial artery in the index finger of the right hand, and a radial vein in the right forearm. Taking advantage of the handheld probe, our method can potentially be used to monitor blood flow speed in the clinic and at the bedside.

Additional Information

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Manuscript Received: 19 JUN 2015. Manuscript Revised: 15 SEP 2015. Manuscript Accepted: 26 SEP 2015. Version of Record online: 30 OCT 2015.

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Supplemental Material - jbio201500181-sup-0001-author-biographies.pdf

Supplemental Material - jbio201500181-sup-0002-video_1.avi

Supplemental Material - jbio201500181-sup-0003-video_2.avi

Supplemental Material - jbio201500181-sup-0004-video_3.avi


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