Published 1979
| Version Published
Journal Article
Open
Production of a Discrete, Infectious, Double-stranded DNA by Reverse Transcription in Virions of Moloney Murine Leukemia Virus
Abstract
One of the most unique viral replication schemes is that of the retroviruses (a class that includes the RNA tumor viruses). These viruses synthesize a double-stranded (DS) DNA copy of their single-stranded (SS) RNA genome as the initial event following infection of susceptible cells (see Weinberg 1977). The details of this process—called reverse transcription—are still obscure, but the general outlines have become clear during the last few years.
Additional Information
© 1979 Cold Spring Harbor Laboratory Press. The Authors acknowledge that six months after the full-issue publication date, the Article will be distributed under a Creative Commons CC-BY-NC License (Attribution-NonCommercial 4.0 International License, http://creativecommons.org/licenses/by-nc/4.0/). We are grateful to the M.I.T. Cell Culture Facility for providing the virus that made these studies possible. This work was supported by grants from the National Cancer Institute and by a contract from the Virus Cancer Program of the National Cancer Institute. D. B. is a Research Professor of the American Cancer Society. E. G. is a Dr. Chaim Weizmann postdoctoral fellow. F. Y. is a Special Fellow of the Leukemia Society of America.Attached Files
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Additional details
Identifiers
- Eprint ID
- 74221
- Resolver ID
- CaltechAUTHORS:20170213-071350586
Funding
- National Cancer Institute
- NIH
- American Cancer Society
- Leukemia Society of America
- Weizmann Institute
Dates
- Created
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2017-02-13Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field