Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published November 27, 2006 | Accepted Version
Journal Article Open

The synthesis of C-3β functionalized indoles via a hydroboration/Suzuki–Miyaura coupling sequence


A method for the functionalization of C-3β of vinyl indoles is described. The procedure involves a hydroboration, followed by a Suzuki–Miyaura cross-coupling with the intermediate alkyl borane. Triflates, bromides, and iodides are suitable coupling partners, allowing access to a variety of elaborated indole compounds.

Additional Information

© 2006 Elsevier Ltd. Received 1 September 2006, Accepted 21 September 2006, Available online 13 October 2006. The authors wish to thank the NIH-NIGMS (R01 GM65961-01), Bristol-Myers Squibb Company (graduate fellowship to E.M.F.), the NSF (graduate fellowship to E.M.F.), the Dreyfus Foundation, Merck Research Laboratories, Research Corporation, Abbott Laboratories, Pfizer, Amgen, GlaxoSmithKline, Lilly, and Johnson and Johnson for their generous financial support.

Attached Files

Accepted Version - nihms-13692.pdf


Files (54.6 kB)
Name Size Download all
54.6 kB Preview Download

Additional details

August 19, 2023
October 23, 2023