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Published July 15, 2003 | Published
Journal Article Open

Optical-fiber-based Mueller optical coherence tomography


An optical-fiber-based multichannel polarization-sensitive Mueller optical coherence tomography (OCT) system was built to acquire the Jones or Mueller matrix of a scattering medium, such as biological tissue. For the first time to our knowledge, fiber-based polarization-sensitive OCT was dynamically calibrated to eliminate the polarization distortion caused by the single-mode optical fiber in the sample arm, thereby overcoming a key technical impediment to the application of optical fibers in this technology. The round-trip Jones matrix of the sampling fiber was acquired from the reflecting surface of the sample for each depth scan (A scan) with our OCT system. A new rigorous algorithm was then used to retrieve the calibrated polarization properties of the sample. This algorithm was validated with experimental data. The skin of a rat was imaged with this fiber-based system.

Additional Information

© 2003 Optical Society of America. Received January 8, 2003. Thanks to Geng Ku for assistance in machining mechanical components for this study. This project was sponsored in part by National Institutes of Health grants R21 EB00319-02 and R01 EB000712, by National Science Foundation grant BES-9734491, and by Texas Higher Education Coordinating Board grant 000512-0063-2001.

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