Published August 1977 | Version public
Journal Article Open

Morphogenesis of poliovirus. IV. existence of particles sedimenting at 150S and having the properties of provirion

Abstract

An apparent precursor to the poliovirion that cosediments with the virion at 150S was identified by its content of VP-0. It has properties previously associated with the provirion, a structure that sedimented at 125S, and it may be an alternate form of provirion. Like virions, the 150S precursor binds to and elutes from cells, after which it sediments at about 125S.

Additional Information

Copyright © 1977 by the American Society for Microbiology. Received for publication 1 February 1977 This work was supported by Public Health Service grant A108388 from the National Institute of Allergy and Infectious Diseases and grants CA 12174 and CA 14051 from the National Cancer Institute. D. B. is a Research Professor of the American Cancer Society.

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