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Published September 28, 1998 | Published
Journal Article Open

Effect of molecular concentrations in tissue-simulating phantoms on images obtained using diffuse reflectance polarimetry


We have investigated the possibility of using diffuse reflectance polarimetry to detect changes caused by different molecular compounds and concentrations in tissue-simulating phantoms. The effects of glucose, β-alanine and l-lysine at different concentrations in turbid media have been investigated separately. This approach is based on the effect of optical properties on the polarization state of light. The results show that this method has potential for determining changes in molecular concentrations in highly scattering biological media from polarization images.

Additional Information

© 1998 Optical Society of America. Received July 03, 1998; Revised September 22, 1998. We thank A. Hebert, K. Wyly and J. Keller for their assistance during the experiments. This project is sponsored in part by the Office of VP for Research at Texas A&M University, the Whitaker Foundation, and the National Institute of Health grants R29 CA68562 & R01 CA71980.

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