Published September 1971 | Version Published
Journal Article Open

Clock mutants of Drosophila melanogaster

Abstract

Three mutants have been isolated in which the normal 24-hour rhythm is drastically changed. One mutant is arrhythmic; another has a period of 19 hr; a third has a period of 28 hr. Both the eclosion rhythm of a population and the locomotor activity of individual flies are affected. All these mutations appear to involve the same functional gene on the X chromosome.

Additional Information

© 1971 by the National Academy of Sciences. Contributed by Seymour Benzer, July 2, 1971. This work was supported by a grant from the National Science Foundation to S.B. and a National Science Foundation predoctoral fellowship to R.K. We thank Dr. Colin Pittendrigh for enlightening discussions and for the loan of several bang boxes, Dr. Yoshiki Hotta for design and construction of the activity detectors, and Barbara Stewart for help with the mapping experiments.

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Identifiers

PMCID
PMC389363
Eprint ID
7605
Resolver ID
CaltechAUTHORS:KONpnas71

Funding

NSF Graduate Research Fellowship

Dates

Created
2007-03-13
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Updated
2023-06-01
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