Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published December 22, 2004 | public
Journal Article

Dynamics of Ordered Water in Interfacial Enzyme Recognition: Bovine Pancreatic Phospholipase A2


Slippery when wet: Water molecules at the interface between a protein (e.g. bovine pancreatic phospholipase A2) and a micellar substrate act as a lubricant and facilitate movement and binding of the protein at the surface (see picture). Studies of the hydration dynamics before and after complexation reveal that these interactions are crucial for enzymatic function.

Additional Information

© 2004 Wiley-VCH Verlag GmbH & Co. Received: September 26, 2003. Published Online: December 8 Dec 2003. Financial support from the National Science Foundation is acknowledged.

Additional details

August 22, 2023
October 20, 2023