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Published August 2012 | public
Journal Article

Protein folding – simplicity in complexity


Understanding and predicting protein folding would elucidate how misfolded proteins cause aggregation and amyloid formation, for example in Alzheimer's disease. Despite the seemingly bewildering complexity of protein biology, simple analytic models can still capture the basic physics and predict the fundamental limits for protein domain size and folding speed.

Additional Information

© 2012 by Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Received 29 June 2012, accepted 2 July 2012. Published online 23 July 2012.

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