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Published December 21, 2006 | public
Journal Article

Thermoacoustic tomography with correction for acoustic speed variations


Thermoacoustic tomography (TAT) is a technique that measures microwave-induced thermoacoustic waves at the boundary of biological tissue and generates images of internal microwave absorption distributions from the measurements. Existing reconstruction algorithms for TAT are based on the assumption that the acoustic properties in the tissue are homogeneous. Biological tissue, however, has heterogeneous acoustic properties, which lead to distortion and blurring of small buried objects in the reconstructed images. In this paper we develop a correction method based on ultrasonic transmission tomography (UTT) to improve the image quality of TAT. Numerical simulations and phantom experiments verify the effectiveness of this correction method.

Additional Information

© 2006 IOP Publishing Ltd. Received 5 September 2006, in final form 19 October 2006. Published 28 November 2006. We thank Geng Ku for assistance with the experimental set-up. The work was supported by the National Institutes of Health grants R01 EB000712 and R01 NS46214.

Additional details

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October 23, 2023