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Published August 2002 | public
Journal Article

Pulsed-microwave-induced thermoacoustic tomography: Filtered backprojection in a circular measurement configuration

Abstract

Our study on pulsed-microwave-induced thermoacoustic tomography in biological tissues is presented. A filtered backprojection algorithm based on rigorous theory is used to reconstruct the cross-sectional image from a thermoacoustic measurement in a circular configuration that encloses the sample under study. Specific details describing the measurement of thermoacoustic waves and the implementation of the reconstruction algorithm are discussed. A two-dimensional (2D) phantom sample with 2 mm features can be imaged faithfully. Through numerical simulation, the full width half-maximum (FWHM) of the point-spread function (PSF) is calculated to estimate the spatial resolution. The results demonstrate that the circular measurement configuration combined with the filtered backprojection method is a promising technique for detecting small tumors buried in biological tissues by utilizing microwave absorption contrast and ultrasound spatial resolution (∼mm).

Additional Information

© 2002 American Association of Physicists in Medicine. Received 12 December 2001; accepted for publication 7 May 2002; published 16 July 2002. This project was sponsored in part by the U.S. Army Medical Research and Material Command Grant No. DAMD17-00-1-0455, the National Institutes of Health Grant No. R01 CA71980, the National Science Foundation Grant No. BES-9734491, and Texas Higher Education Coordinating Board Grant No. ARP 000512-0123-1999.

Additional details

Created:
August 19, 2023
Modified:
October 24, 2023