Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published December 2, 1999 | public
Journal Article

Synthesis of Trisubstituted Alkenes via Olefin Cross-Metathesis


Trisubstituted alkenes have been prepared for the first time via intermolecular olefin cross-metathesis, using 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene ruthenium alkylidene complexes 3a,b in good yields with moderate E selectivity. In addition, protected alcohols near the geminal disubstituted olefin improve reactivity for cross-metathesis.

Additional Information

© 1999 American Chemical Society. Received September 7, 1999. Publication Date (Web): November 2, 1999. Support has been generously provided by the National Institutes of Health. The authors thank Andrew G. Myers, Matthias Scholl, Thomas A. Kirkland, Helen E. Blackwell, and Daniel J. O'Leary for useful discussions and encouragement. The authors also wish to thank Richard Pederson for a generous supply of compound 8.

Additional details

August 19, 2023
October 18, 2023