Enantioselective Ni-catalyzed reductive cross-coupling reactions

Nickel-catalyzed reductive cross-coupling reactions have emerged as direct bond formation. These reactions typically tolerate an array of functional groups, and employ inexpensive, earth abundant metals as stoichiometric reductants. May require the use of pre-generated organometallic reagents. In order to realize the catalyzed reductive cross-coupling reactions, it is crit. to develop enantioselective transformations. This seminar will describe our recent successes in the develop enantioselective cross-coupling reactions.