CaltechAUTHORS
Published July 15, 2011 | Version Accepted Version
Journal Article Open

The FaceBase Consortium: A comprehensive program to facilitate craniofacial research

Creators

Abstract

The FaceBase Consortium consists of ten interlinked research and technology projects whose goal is to generate craniofacial research data and technology for use by the research community through a central data management and integrated bioinformatics hub. Funded by the National Institute of Dental and Craniofacial Research (NIDCR) and currently focused on studying the development of the middle region of the face, the Consortium will produce comprehensive datasets of global gene expression patterns, regulatory elements and sequencing; will generate anatomical and molecular atlases; will provide human normative facial data and other phenotypes; conduct follow up studies of a completed genome-wide association study; generate independent data on the genetics of craniofacial development, build repositories of animal models and of human samples and data for community access and analysis; and will develop software tools and animal models for analyzing and functionally testing and integrating these data. The FaceBase website (http://www.facebase.org) will serve as a web home for these efforts, providing interactive tools for exploring these datasets, together with discussion forums and other services to support and foster collaboration within the craniofacial research community.

Additional Information

© 2011 Elsevier Inc. Received 25 January 2011; revised 23 February 2011; accepted 24 February 2011. Available online 31 March 2011. The FaceBase Consortium thanks the many investigators and staff members for working collaboratively and untiringly toward fulfilling the goals of the program. In particular,we appreciate the vision and support of Dr. Lawrence A. Tabak, former Director of the National Institute of Dental and Craniofacial Research (NIDCR), in enabling this effort. We thank the NIDCR Program Staff for their advice in implementing FaceBase and suggestions for this manuscript (Program Official: Steven Scholnick; Project Scientists: Emily Harris, Nadya Lumelsky, Lillian Shum). We are very grateful to Carolyn Randolph for editorial assistance inpreparing this paper. Projects comprising the FaceBase Consortium are supported by grants from the NIDCR, U01-DE20049 (S.S.P., B.A., P.A.T), U01-DE20050 (L.S., M.L.C., J.F.B), U01-DE20052 (L.R.B.D., S.A.M.), U01-DE20054 (R.A.S.), U01-DE020057 (J.C.M., M.L.M., H.H. M.D.), U01-DE20060 (A.V.), U01-DE20063 (S.E.F.), U01-DE20065 (Y.C., J.I.), U01-DE20073 (T.H.B.), U01-DE20076 (D.E.C., K.B.A., J.H.P.) and U01-DE20078 (S.M.W., M.L.M. M.L.C).

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Additional details

Identifiers

PMCID
PMC3440302
Eprint ID
24443
Resolver ID
CaltechAUTHORS:20110718-100407556

Funding

National Institute of Dental and Cranofacial Research (NIDCR)
U01-DE20049
National Institute of Dental and Cranofacial Research (NIDCR)
U01-DE20050
National Institute of Dental and Cranofacial Research (NIDCR)
U01-DE20052
National Institute of Dental and Cranofacial Research (NIDCR)
U01- DE20054
National Institute of Dental and Cranofacial Research (NIDCR)
U01-DE020057
National Institute of Dental and Cranofacial Research (NIDCR)
U01-DE20060
National Institute of Dental and Cranofacial Research (NIDCR)
U01-DE20063
National Institute of Dental and Cranofacial Research (NIDCR)
U01-DE20065
National Institute of Dental and Cranofacial Research (NIDCR)
U01- DE20073
National Institute of Dental and Cranofacial Research (NIDCR)
U01-DE20076
National Institute of Dental and Cranofacial Research (NIDCR)
U01-DE20078

Dates

Created
2011-07-18
Created from EPrint's datestamp field
Updated
2021-11-09
Created from EPrint's last_modified field