1
TABLE S2
, Related to Figure
S4
.
Projections of Tac2
+
cells in dBNSTa, DMH and
CEA
Injection
region
Projection
region
D
ensity
% Total
projection*
Central amygdalar nucleus (CEA)
0.0099
1.492312
Globus pallidus, internal segment (GPi)
0.006
0.904432
Bed nuclei of the stria
terminalis (BST)
0.0065
0.979801
Bed nucleus of the anterior commissure (BAC)
0.0374
5.637624
Subparafascicular nucleus, parvicellular part (SPFp)
0.0371
5.592403
Reticular nucleus of the thalamus (RT)
0.0077
1.160687
Vascular organ of the lamina
terminalis (OV)
0.0103
1.552608
Supramammillary nucleus (SUM)
0.0058
0.874284
Tuberomammillary nucleus, ventral part (TMv)
0.0076
1.145614
Paraventricular hypothalamic nucleus, descending
division (PVHd)
0.0066
0.994875
Lateral hypothalamic area
(LHA)
0.0082
1.236057
Lateral preoptic area (LPO)
0.0236
3.557431
Preparasubthalamic nucleus (PST)
0.0162
2.441966
Parasubthalamic nucleus (PSTN)
0.0714
10.76274
Subthalamic nucleus (STN)
0.0379
5.712994
Tubueral nucleus (TU)
0.012
1.808863
Midbrain trigeminal nucleus (MEV)
0.0124
1.869159
Ventral tegmental area (VTA)
0.0176
2.653
Midbrain reticular nucleus, retrorubral area (RR)
0.0205
3.090142
dBNST
a
Midbrain reticular nucleus (MRN)
0.0325
4.899005
Periaqueductal gray (PAG)
0.0171
2.57763
Cuneiform nucleus (CUN)
0.0092
1.386795
Edinger
-
Westphal nucleus (EW)
0.0071
1.070244
Substantia nigra, compact part (SNc)
0.0123
1.854085
Pedunculopontine nucleus (PPN)
0.0239
3.602653
Rostral linear nucleus raphe (RL)
0.0195
2.939403
Central linear nucleus raphe (CLI)
0.0169
2.547483
Dorsal nucleus raphe (DR)
0.0098
1.477238
Parabrachial nucleus (PB)
0.006
0.904432
Barrington’s nucleus (B)
0.0084
1.266204
Supratrigeminal nucleus (SUT)
0.0095
1.432017
External cuneate nucleus
(ECU)
0.0095
1.432017
Nucleus ambiguus (MB)
0.0076
1.145614
Lateral reticular nucleus (LRN)
0.0136
2.050045
Magnocellular reticular nucleus (MARN)
0.0074
1.115466
Parvicellular reticular nucleus (PARN)
0.0136
2.050045
Paragigantocellular
reticular nucleus, lateral part
(PGRNl)
0.0067
1.009949
2
Parapyramidal nucleus (PPY)
0.01
1.507386
Nucleus raphe magnus (RM)
0.0139
2.095267
Nucleus raphe pallidus (RPA)
0.0198
2.984625
Nucleus raphe obscurus (RO)
0.0161
2.426892
Induseum griseum
(IG)
0.0007
2.991453
Hypothalamus (HY)
0.0008
3.418803
Dorsal medial hypothalamus (DMH)
0.0053
22.64957
Ventrolateral preoptic nucleus (VLPO)
0.0005
2.136752
Supramammallary nucleus (SUM)
0.0008
3.418803
Ventral tuberomammallary nucleus (TMv)
0.001
4.273504
DMH
Dorsal premammillary nucleus (PMd)
0.0028
11.96581
Ventral premammillary nucleus (PMv)
0.0026
11.11111
Posterior hypothalamic nucleus (PH)
0.005
21.36752
Lateral hypothalamic area (LHA)
0.0011
4.700855
Parasubthalamic
nucleus (PSTN)
0.0007
2.991453
Tuberal nucleus (TU)
0.0011
4.700855
Medulla (MY)
0.0001
0.42735
Nucleus raphe pallidus (RPA)
0.0009
3.846154
Central amygdalar nucleus (CEA)
0.0736
4.920115
Pallidum (PAL)
0.0201
1.343673
Globus pallidus,
internal segment (GPi)
0.0363
2.426633
Substantia innominate (SI)
0.0248
1.657865
Subparafascicular nucleus, magnocellular part
(SPFm)
0.021
1.403837
Subparafascicular nucleus, parvicellular part (SPFp)
0.048
3.208771
Subparafascicular area (SPA)
0.0238
1.591015
Peripeduncular nucleus (PP)
0.0215
1.437262
Reticular nucleus of the thalamus (RT)
0.0226
1.510796
Paraventricular hypothalamic nucleus, descending
division (PVHd)
0.0294
1.965372
Lateral hypothalamic area (LHA)
0.0352
2.353098
Lateral preoptic area (LPO)
0.0246
1.644495
Preparasubthalamic nucleus (PST)
0.137
9.158366
CEA
Parasubthalamic nucleus (PSTN)
0.103
6.885487
Subthalamic nucleus (STN)
0.0544
3.636607
Zona incerta (ZI)
0.0217
1.450632
Midbrain trigeminal nucleus
(MEV)
0.0411
2.74751
Ventral tegmental area (VTA)
0.0382
2.553647
Midbrain reticular nucleus, retrorubral area (RR)
0.0857
5.728993
Midbrain reticular nucleus (MRN)
0.0471
3.148606
Periaqueductal gray (PAG)
0.0293
1.958687
Edinger
-
Westphal
nucleus (EW)
0.0208
1.390467
Trochlear nucleus (IV)
0.0348
2.326359
3
Substantia nigra, compact part (SNc)
0.0678
4.532389
Pedunculopontine nucleus (PPN)
0.0455
3.041647
Parabrachial nucleus (PB)
0.028
1.871783
Pontine reticular nucleus, caudal
part (PRNc)
0.0207
1.383782
Supratrigeminal nucleus (SUT)
0.0447
2.988168
Tegmental reticular nucleus (TRN)
0.0203
1.357043
Accessory facial motor nucleus (ACVII)
0.0435
2.907948
CEA
Inferior salivatory nucleus (ISN)
0.0239
1.5977
Magnocellular
reticular nucleus (MARN)
0.0437
2.921318
Parvicellular reticular nucleus (PARN)
0.0348
2.326359
Parapyramidal nucleus (PPY)
0.0336
2.246139
Nucleus raphe magnus (RM)
0.043
2.874524
Nucleus raphe pallidus (RPA)
0.0242
1.617755
Nucleus raphe
obscurus (RO)
0.0282
1.885153
Data obtained from injection of Cre
-
dependent GFP
-
expressing AAV1 into indicated
regions of Tac2
-
IRES
-
Cre mice;
Mouse Connectivity Atlas, Allen Institute for Brain
Science
.
dBNST: Experiment #265138021;
density cutoff: 0
.0058
DMH: Experiment #300927483;
density cutoff: 0
.0005
CeA: Experi
ment #241279261; density cutoff:
0
.02
*projection
density
% normalized to
total density of
unilateral projections
for each
injected region
(
above respective cutoffs
).