Published January 1, 1970 | Version public
Journal Article Open

Nuclear magnetic resonance spectroscopy: 13C spectra of some common nucleotides

Abstract

Natural-abundance 13C nuclear magnetic resonance spectra of ten common nucleotides in neutral, aqueous solutions have been determined and interpreted. The spectra of two of these substances were also determined in acidic solutions, and several of the carbon chemical shifts were found to depend markedly on pH. Within the limited range of concentrations employed, there were observed no carbon chemical-shift changes which could be ascribed to base-stacking or base-pairing phenomena.

Additional Information

© 1970 by the National Academy of Sciences. Communicated October 20, 1969. Supported by the Public Health Service, Research Grant GM-11072-07 from the Division of General Medical Sciences. Contribution no. 3938, Gates and Crellin Laboratories of Chemistry, California Institute of Technology. [D.E.D. was a] National Institutes of Health Postdoctoral Fellow, 1967-1970.

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2007-10-29
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