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Published October 7, 2009 | Accepted Version
Journal Article Open

Photoacoustic tomography and sensing in biomedicine


Photoacoustics has been broadly studied in biomedicine, for both human and small animal tissues. Photoacoustics uniquely combines the absorption contrast of light or radio frequency waves with ultrasound resolution. Moreover, it is non-ionizing and non-invasive, and is the fastest growing new biomedical method, with clinical applications on the way. This review provides a brief recap of recent developments in photoacoustics in biomedicine, from basic principles to applications. The emphasized areas include the new imaging modalities, hybrid detection methods, photoacoustic contrast agents and the photoacoustic Doppler effect, as well as translational research topics.

Additional Information

© 2009 Institute of Physics and Engineering in Medicine. Received 3 February 2009; In final form 4 August 2009; Published 1 September 2009. This work has be supported in part by National Institutes of Health grants R01 EB000712, R01 NS46214 (Bioengineering Research Partnerships), R01 EB008085 and U54 CA136398 (Network for Translational Research). LW has a financial interest in Microphotoacoustics, Inc., and Endra, Inc., which, however, did not support this work.

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October 20, 2023