Published July 3, 2025 | Version Published
Journal Article Open

A systematic review of flotation-restricted environmental stimulation therapy (REST)

  • 1. ROR icon Abbott (United States)
  • 2. ROR icon Chapman University
  • 3. ROR icon University of California, Los Angeles
  • 4. ROR icon California Institute of Technology

Abstract

Background:

Restricted Environmental Stimulation Therapy (REST) is a therapeutic technique that involves immersing an individual in an environment with minimal sensory input or stimulation. The goal of REST is to induce a state of relaxation that is deeper than what can be achieved through other forms of relaxation techniques. Research suggests that REST can help reduce anxiety, alleviate chronic pain, improve sleep, and enhance creativity and cognitive function. Flotation-REST is a popular type of REST that utilizes an enclosed tank filled with buoyant saltwater to facilitate relaxation. This study aimed to synthesize the evidence on studies that investigate the effects of flotation-REST.

Methods:

We used Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) to survey the flotation-REST literature starting from the earliest papers we could find, in 1960, until May 2024. This search was conducted on 23 May 2024 within the Google Scholar and PubMed databases. Journal and conference papers, as well as electronic preprints, that used flotation-REST in their methods, and that were written in English were included; non-original research papers (e.g., review papers, book chapters, and papers solely on types of REST other than flotation-REST (e.g., chamber-REST) were excluded. From each eligible paper, we extracted information regarding the participant sample, application of flotation-REST, experimental design, treatment delivery method, questionnaires and tools, and study results.

Results:

In total, we found 63 studies that included 1,838 participants. We propose that the application of flotation-REST can be divided into nine main categories: pain, athletic performance, physiology, stress, consciousness, psychology, creativity, clinical anxiety, sleep, smoking cessation, and other miscellaneous applications. In general, flotation-REST was found to bring about positive effects on pain, athletic performance, stress, mental well-being, and clinical anxiety, while having limited to no effect on sleep-related disorders and smoking cessation.

Conclusion:

This paper provides a comprehensive overview of the current research on flotation-REST, highlights ongoing limitations in the literature, and outlines potential areas for future research. While flotation-REST appears to induce various benefits for physical and mental well-being, particularly when it comes to managing states like pain and stress, more research is needed to better understand the mechanisms underlying these effects and to identify optimal treatment protocols for different populations. A limitation of this paper is the relatively small number of studies available for review, which limits the generalizability of certain findings and highlights the need for additional research in this area.

Copyright and License

© The Author(s) 2025. This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

Acknowledgement

We thank Amir Raz for his guidance and support during the initial stages of this project.

Funding

The publication received support from a joint grant from the John Templeton Foundation and the Fetzer Institute. The views expressed herein are solely those of the author(s) and do not necessarily represent the opinions of NINDS, the John Templeton Foundation, or the Fetzer Institute.

Ethics

Ethics approval and consent to participate:

NA.

Consent for publication:

We confirm that there are no conflicts of interest to disclose related to this work. We also attest that this manuscript has not been published elsewhere and is not under consideration by any other journal or conference.

Competing interests:

The authors declare no competing interests.

Registration and protocol:

This study was not registered, and a review protocol was not prepared.

Supplemental Material

Supplementary Material 1

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Related works

Describes
Journal Article: PMC12224670 (PMCID)
Journal Article: https://rdcu.be/ewDSU (ReadCube)
Journal Article: 40611079 (PMID)
Is new version of
Discussion Paper: 10.1101/2023.11.29.23299203 (DOI)
Is supplemented by
Supplemental Material: https://static-content.springer.com/esm/art%3A10.1186%2Fs12906-025-04973-0/MediaObjects/12906_2025_4973_MOESM1_ESM.docx (URL)

Funding

John Templeton Foundation
Fetzer Institute

Dates

Accepted
2025-06-11
Available
2025-07-03
Published

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Caltech groups
Division of Biology and Biological Engineering (BBE)
Publication Status
Published