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Items where Person is "Nussenzweig-M-C"

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Number of items: 49.

2020

Hoffmann, Magnus A. G. and Bar-On, Yotam and Yang, Zhi et al. (2020) Nanoparticles presenting clusters of CD4 expose a universal vulnerability of HIV-1 by mimicking target cells. Proceedings of the National Academy of Sciences of the United States of America, 117 (31). pp. 18719-18728. ISSN 0027-8424. https://resolver.caltech.edu/CaltechAUTHORS:20200720-150827662

Barnes, Christopher O. and West, Anthony P., Jr. and Huey-Tubman, Kathryn E. et al. (2020) Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies. Cell . ISSN 0092-8674. (In Press) https://resolver.caltech.edu/CaltechAUTHORS:20200601-100510853

Esswein, Shannon R. and Gristick, Harry B. and Jurado, Andrea et al. (2020) Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody. Proceedings of the National Academy of Sciences of the United States of America, 117 (18). pp. 9865-9875. ISSN 0027-8424. PMCID PMC7211955 . https://resolver.caltech.edu/CaltechAUTHORS:20200422-131710102

Van Rompay, Koen K. A. and Coffey, Lark L. and Kapoor, Tania et al. (2020) A Combination of Two Human Monoclonal Antibodies Limits Fetal Damage by Zika Virus in Macaques. Proceedings of the National Academy of Sciences of the United States of America, 117 (14). pp. 7981-7989. ISSN 0027-8424. PMCID PMC7149495. https://resolver.caltech.edu/CaltechAUTHORS:20200203-091204189

2019

Schoofs, Till and Barnes, Christopher O. and Suh-Toma, Nina et al. (2019) Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity, 50 (6). pp. 1513-1529. ISSN 1074-7613. PMCID PMC6591006. https://resolver.caltech.edu/CaltechAUTHORS:20190521-102845469

2018

Keeffe, Jennifer R. and Van Rompay, Koen K. A. and Olsen, Priscilla C. et al. (2018) A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates. Cell Reports, 25 (6). pp. 1385-1394. ISSN 2211-1247. PMCID PMC6268006. https://resolver.caltech.edu/CaltechAUTHORS:20181106-092448645

Wang, Haoqing and Barnes, Christopher O. and Yang, Zhi et al. (2018) Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion. Cell Host & Microbe, 24 (4). pp. 579-592. ISSN 1931-3128. PMCID PMC6185872. https://resolver.caltech.edu/CaltechAUTHORS:20181010-142117602

Barnes, Christopher O. and Wang, Haoqing and Yang, Zhi et al. (2018) A Co-receptor-mimicking Antibody Stabilizes the Displaced V1V2 Loops in a Partially Open sCD4-bound HIV-1 Envelope Complex. AIDS Research and Human Retroviruses, 34 (S1). p. 131. ISSN 0889-2229. https://resolver.caltech.edu/CaltechAUTHORS:20181116-084257854

Gristick, Harry and van Schooten, Jelle and Hartweger, Harald et al. (2018) Engineering HIV Immunogens to Elicit IOMA-like Antibodies Targeting the CD4 Binding Site. AIDS Research and Human Retroviruses, 34 (S1). p. 59. ISSN 0889-2229. https://resolver.caltech.edu/CaltechAUTHORS:20181116-085049231

Escolano, Amelia and Gristick, Harry B. and Gautam, Rajeev et al. (2018) Sequential Immunization Strategies to Elicit HIV-1 bNAbs in Animal Models With a Polyclonal B Cell Repertoire. AIDS Research and Human Retroviruses, 34 (S1). p. 331. ISSN 0889-2229. https://resolver.caltech.edu/CaltechAUTHORS:20181116-085739103

Barnes, Christopher O. and Gristick, Harry B. and Freund, Natalia T. et al. (2018) Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope. Nature Communications, 9 . Art. No. 1251. ISSN 2041-1723. PMCID PMC5871869. https://resolver.caltech.edu/CaltechAUTHORS:20180330-082805151

2017

Wang, Haoqing and Gristick, Harry B. and Scharf, Louise et al. (2017) Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies. eLife, 6 . Art. No. e27389. ISSN 2050-084X. PMCID PMC5472438. https://resolver.caltech.edu/CaltechAUTHORS:20170530-103124593

2016

Diskin, Ron and Bjorkman, Pamela J. and Nussenzweig, Michel et al. (2016) Antibodies directed toward the HIV-1 GP120 CD4 binding site with increased potency and breadth. Patent number: US9493549B2. https://resolver.caltech.edu/CaltechAUTHORS:20171025-161147200

Gristick, Harry B. and von Boehmer, Lotta and West, Anthony P., Jr. et al. (2016) Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site. Nature Structural & Molecular Biology, 23 (10). pp. 906-915. ISSN 1545-9985. PMCID PMC5127623. https://resolver.caltech.edu/CaltechAUTHORS:20160728-151253831

Gristick, Harry and von Boehmer, Lotta and West, Anthony, Jr. et al. (2016) Structure of a Natively-glycosylated HIV-1 Env Reveals a New Mode for VH1-2 Antibody Recognition of the CD4 Binding Site Relevant to Vaccine Design. AIDS Research and Human Retroviruses, 32 (Suppl. 1). p. 62. ISSN 0889-2229. https://resolver.caltech.edu/CaltechAUTHORS:20161128-145837422

Schoofs, Till and Klein, Florian and Braunschweig, Malte et al. (2016) HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1. Science, 352 (6288). pp. 997-1001. ISSN 0036-8075. PMCID PMC5151174. https://resolver.caltech.edu/CaltechAUTHORS:20160601-145651018

Scharf, Louise and West, Anthony P. , Jr. and Sievers, Stuart A. et al. (2016) Structural basis for germline antibody recognition of HIV-1 immunogens. eLife, 5 . Art. No. e13783. ISSN 2050-084X. PMCID PMC4811768. https://resolver.caltech.edu/CaltechAUTHORS:20160328-112605894

Morgand, Marion and Bouvin-Pley, Mélanie and Plantier, Jean-Christophe et al. (2016) V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1. Journal of Acquired Immune Deficiency Syndromes, 71 (3). pp. 237-245. ISSN 1525-4135. PMCID PMC4770367. https://resolver.caltech.edu/CaltechAUTHORS:20160222-083645431

2015

Freund, Natalia T. and Horwitz, Joshua A. and Nogueira, Lilian et al. (2015) A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo. PLoS Pathogens, 11 (10). Art. No. e1005238. ISSN 1553-7366. PMCID PMC4627763. https://resolver.caltech.edu/CaltechAUTHORS:20151109-110339907

Dosenovic, Pia and von Boehmer, Lotta and Escolano, Amelia et al. (2015) Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice. Cell, 161 (7). pp. 1505-1515. ISSN 0092-8674. PMCID PMC4604566. https://resolver.caltech.edu/CaltechAUTHORS:20150701-123923449

Galimidi, Rachel P. and Klein, Joshua S. and Politzer, Maria S. et al. (2015) Intra-Spike Crosslinking Overcomes Antibody Evasion by HIV-1. Cell, 160 (3). pp. 433-446. ISSN 0092-8674. PMCID PMC4401576. https://resolver.caltech.edu/CaltechAUTHORS:20150203-085327952

2014

Bouvin-Pley, M. and Morgand, M. and Meyer, L. et al. (2014) Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: a comprehensive study using the most potent and broadly neutralizing monoclonal antibodies. Journal of Virology, 88 (23). pp. 13910-13917. ISSN 0022-538X. PMCID PMC4248973. https://resolver.caltech.edu/CaltechAUTHORS:20141001-132423634

Klein, Florian and Nogueira, Lilian and Nishimura, Yoshiaki et al. (2014) Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants. Journal of Experimental Medicine, 211 (12). pp. 2361-2372. ISSN 0022-1007. PMCID PMC4235636. https://resolver.caltech.edu/CaltechAUTHORS:20141117-100446185

Scheid, Johannes and Nussenzweig, Michel and Bjorkman, Pamela J. et al. (2014) Human immunodeficiency virus neutralizing antibodies and methods of use thereof [APPLICATION]. Patent number: US20140328862A1. https://resolver.caltech.edu/CaltechAUTHORS:20171025-163159394

Bouvin-Pley, Mélanie and Morgand, Marion and Moreau, Alain et al. (2014) Adaptation of HIV-1 Envelope Glycoprotein gp120 to Humoral Immunity over the Course of the Epidemic. AIDS Research and Human Retroviruses, 30 (S1). A224. ISSN 0889-2229. https://resolver.caltech.edu/CaltechAUTHORS:20150211-074826079

Sievers, Stuart A. and Patel, Sonal N. and Bennett, Kathleen et al. (2014) Engineering Antibodies to Enhance Activity and Increase Half-life. AIDS Research and Human Retroviruses, 30 (S1). A210. ISSN 0889-2229. https://resolver.caltech.edu/CaltechAUTHORS:20150211-082514507

Nishimura, Yoshiaki and Shingai, Masashi and Donau, Olivia K. et al. (2014) Preexposure passive transfer predicts plasma antibody levels prevent HIV-I aquisition. Journal of Medical Primatology, 43 (5). p. 378. ISSN 0047-2565. https://resolver.caltech.edu/CaltechAUTHORS:20141124-131258070

Scharf, Louise and Scheid, Johannes F. and Lee, Jeong-Hyun et al. (2014) Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike. Cell Reports, 7 (3). pp. 785-795. ISSN 2211-1247. PMCID PMC4109818. https://resolver.caltech.edu/CaltechAUTHORS:20140505-103212905

West, Anthony P., Jr. and Scharf, Louise and Scheid, Johannes F. et al. (2014) Structural Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy. Cell, 156 (4). pp. 633-648. ISSN 0092-8674. PMCID PMC4041625. https://resolver.caltech.edu/CaltechAUTHORS:20140220-100322233

2013

West, A. P., Jr. and Scharf, L. and Horwitz, J. et al. (2013) Computational Analysis of Anti-HIV-1 Antibody Neutralization Panel Data to Identify Potential Functional Epitope Residues. AIDS Research and Human Retroviruses, 29 (11). A170. ISSN 0889-2229. https://resolver.caltech.edu/CaltechAUTHORS:20131122-104048690

Scharf, L. and West, A. P. and Scheid, J. F. et al. (2013) Structural Basis for HIV-1 gp120 Recognition by a Germ-line Version of a Broadly Neutralizing Antibody. AIDS Research and Human Retroviruses, 29 (11). A11-A12. ISSN 0889-2229. https://resolver.caltech.edu/CaltechAUTHORS:20131122-103725550

Horwitz, Joshua A. and Halper-Stromberg, Ariel and Mouquet, Hugo et al. (2013) HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice. Proceedings of the National Academy of Sciences of the United States of America, 110 (41). pp. 16538-16543. ISSN 0027-8424. PMCID PMC3799352. https://resolver.caltech.edu/CaltechAUTHORS:20131105-095202612

Klein, Florian and Mouquet, Hugo and Dosenovic, Pia et al. (2013) Antibodies in HIV-1 Vaccine Development and Therapy. Science, 341 (6151). pp. 1199-1204. ISSN 0036-8075. PMCID PMC3970325. https://resolver.caltech.edu/CaltechAUTHORS:20131010-092934615

West, Anthony P., Jr. and Scharf, Louise and Horwitz, Joshua et al. (2013) Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues. Proceedings of the National Academy of Sciences of the United States of America, 110 (26). pp. 10598-10603. ISSN 0027-8424. PMCID PMC3696754. https://resolver.caltech.edu/CaltechAUTHORS:20130815-105910867

Diskin, Ron and Klein, Florian and Horwitz, Joshua A. et al. (2013) Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies. Journal of Experimental Medicine, 210 (6). pp. 1235-1249. ISSN 0022-1007. PMCID PMC3674693. https://resolver.caltech.edu/CaltechAUTHORS:20130711-154054415

Scharf, Louise and West, Anthony P., Jr. and Gao, Han et al. (2013) Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody. Proceedings of the National Academy of Sciences of the United States of America, 110 (15). pp. 6049-6054. ISSN 0027-8424. PMCID PMC3625305. https://resolver.caltech.edu/CaltechAUTHORS:20130606-150212765

Diskin, Ron and Sather, D. Noah and Marcovecchio, Paola M. et al. (2013) Overcoming HIV pathways for escape using rationally-designed anti-HIV antibodies. Journal of Acquired Immune Deficiency Syndromes, 62 (S1). p. 49. ISSN 1525-4135. https://resolver.caltech.edu/CaltechAUTHORS:20140310-092725181

Klein, Florian and Diskin, Ron and Scheid, Johannes F. et al. (2013) Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization. Cell, 153 (1). pp. 126-138. ISSN 0092-8674. PMCID PMC3792590. https://resolver.caltech.edu/CaltechAUTHORS:20130517-092438212

2012

Klein, Florian and Halper-Stromberg, Ariel and Horwitz, Joshua A. et al. (2012) HIV therapy by a combination of broadly neutralizing antibodies in humanized mice. Nature, 492 (7427). pp. 118-122. ISSN 0028-0836. PMCID PMC3809838. https://resolver.caltech.edu/CaltechAUTHORS:20130103-133212476

Mouquet, Hugo and Scharf, Louise and Euler, Zelda et al. (2012) Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies. Proceedings of the National Academy of Sciences of the United States of America, 109 (47). E3268-E3277. ISSN 0027-8424. PMCID PMC3511153. https://resolver.caltech.edu/CaltechAUTHORS:20130103-133115442

Pietzsch, John and Gruell, Henning and Bournazos, Stylianos et al. (2012) A mouse model for HIV-1 entry. Proceedings of the National Academy of Sciences of the United States of America, 109 (39). pp. 15859-15864. ISSN 0027-8424. PMCID PMC3465400. https://resolver.caltech.edu/CaltechAUTHORS:20121113-123326208

West, A. P., Jr. and Diskin, R. and Nussenzweig, M. C. et al. (2012) Structural basis for germline gene usage of a potent class of antibodies targeting the CD4 binding site of HIV-1 gp120. Retrovirology, 9 (S2). Art. No. O33. ISSN 1742-4690. PMCID PMC3441645. https://resolver.caltech.edu/CaltechAUTHORS:20121116-082755800

West, Anthony P., Jr. and Diskin, Ron and Nussenzweig, Michel C. et al. (2012) Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120. Proceedings of the National Academy of Sciences of the United States of America, 109 (30). E2983-E2090. ISSN 0027-8424. PMCID PMC3409792. https://resolver.caltech.edu/CaltechAUTHORS:20120907-105238428

2011

Diskin, Ron and Scheid, Johannes F. and Marcovecchio, Paola M. et al. (2011) Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design. Science, 334 (6060). pp. 1289-1293. ISSN 0036-8075. PMCID PMC3232316. https://resolver.caltech.edu/CaltechAUTHORS:20111220-092937610

Scheid, Johannes F. and Mouquet, Hugo and Ueberheide, Beatrix et al. (2011) Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding. Science, 333 (6049). pp. 1633-1637. ISSN 0036-8075. PMCID PMC3351836. https://resolver.caltech.edu/CaltechAUTHORS:20111010-101426546

2004

Jankovic, Mila and Casellas, Rafael and Yannoutsos, Nikos et al. (2004) RAGs and Regulation of Autoantibodies. Annual Review of Immunology, 22 . pp. 485-501. ISSN 0732-0582. https://resolver.caltech.edu/CaltechAUTHORS:JANari04

2000

Liu, Yang and Chirino, Arthur J. and Misulovin, Ziva et al. (2000) Crystal Structure of the Cysteine-Rich Domain of Mannose Receptor Complexed with a Sulfated Carbohydrate Ligand. Journal of Experimental Medicine, 191 (7). pp. 1105-1115. ISSN 0022-1007. PMCID PMC2193177. https://resolver.caltech.edu/CaltechAUTHORS:20111129-160812983

1996

Cortes, Patricia and Weis-Garcia, Frances and Misulovin, Ziva et al. (1996) In vitro V(D)J recombination: Signal joint formation. Proceedings of the National Academy of Sciences of the United States of America, 93 (24). pp. 14008-14013. ISSN 0027-8424. PMCID PMC19485. https://resolver.caltech.edu/CaltechAUTHORS:CORpnas96

1994

Spanopoulou, Eugenia and Roman, Christopher A. J. and Corcoran, Lynn M. et al. (1994) Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice. Genes and Development, 8 (9). pp. 1030-1042. ISSN 0890-9369. https://resolver.caltech.edu/CaltechAUTHORS:20200513-081507377

This list was generated on Fri Aug 7 23:10:08 2020 PDT.