Published April 15, 2013
| public
Journal Article
Development of functional assays for p97/VCP inhibition
Abstract
p97 (also called VCP in metazoans and CDC48 in yeast) is a highly conserved, ubiquitously expressed, and essential AAA ATPase. p97 plays a key role in endoplasmic reticulum-associated degradation of misfolded secretory and membrane proteins as well as ubiquitin-dependent turnover of a subset of cytoplasmic substrates of the ubiquitin-proteasome system.
Additional Information
© 2013 American Association for Cancer Research. Funded by NExT Chemical Biology Consortium, NCI Contract No. HHSN261200800001E.Additional details
- Eprint ID
- 44489
- DOI
- 10.1158/1538-7445.AM2013-2146
- Resolver ID
- CaltechAUTHORS:20140325-082556135
- NExT Chemical Biology Consortium
- National Cancer Institute
- HHSN261200800001E
- Created
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2014-03-25Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field