Lensfree On-chip Microscopy Achieves Accurate Measurement of Yeast Cell Viability and Concentration Using Machine Learning

Creators: Feizi, Alborz; Zhang, Yibo; Greenbaum, Alon; Guziak, Alex; Luong, Michelle; Chan, Raymond Yan Lok; Berg, Brandon; Ozkan, Haydar; Luo, Wei; Wu, Michael; Wu, Yichen; Ozcan, Aydogan

Abstract

Automatic measurement of yeast viability and concentration is achieved by coupling a lensfree on-chip holographic microscope with a machine learning based classification algorithm that counts the number of live/dead cells stained with methylene blue.

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