Primary somatosensory cortex organization for engineering artificial somatosensation

Creators: Lamorie-Foote, Krista¹; Kramer, Daniel R.^{1, 2}; Sundaram, Shivani¹; Cavaleri, Jonathon¹; Gilbert, Zachary D.¹; Tang, Austin M.^{1, 3}; Bashford, Luke^{4, 5}; Liu, Charles Y.¹; Kellis, Spencer¹; Lee, Brian¹

1. University of Southern California
2. University of Colorado Denver
3. The University of Texas Health Science Center at Houston
4. California Institute of Technology
5. Newcastle University

Abstract

Somatosensory deficits from stroke, spinal cord injury, or other neurologic damage can lead to a significant degree of functional impairment. The primary (SI) and secondary (SII) somatosensory cortices encode information in a medial to lateral organization. SI is generally organized topographically, with more discrete cortical representations of specific body regions. SII regions corresponding to anatomical areas are less discrete and may represent a more functional rather than topographic organization. Human somatosensory research continues to map cortical areas of sensory processing with efforts primarily focused on hand and upper extremity information in SI. However, research into SII and other body regions is lacking. In this review, we synthesize the current state of knowledge regarding the cortical organization of human somatosensation and discuss potential applications for brain computer interface. In addition to accurate individualized mapping of cortical somatosensation, further research is required to uncover the neurophysiological mechanisms of how somatosensory information is encoded in the cortex.

Copyright and License

Funding

This research did not receive any specific grant from funding agencies in the pubic, commercial, or not-for-profit sectors.

Contributions

Lamorie-Foote Krista: Conceptualization, Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing. Lee Brian: Conceptualization, Data curation, Methodology, Supervision, Writing – original draft, Writing – review & editing. Bashford Luke: Conceptualization, Data curation, Methodology, Writing – original draft, Writing – review & editing. Tang Austin M.: Conceptualization, Data curation, Methodology, Writing – original draft, Writing – review & editing. Kellis Spencer: Conceptualization, Data curation, Methodology, Supervision, Writing – original draft, Writing – review & editing. Liu Charles Y.: Conceptualization, Data curation, Methodology, Supervision, Writing – original draft, Writing – review & editing. Sundaram Shivani: Conceptualization, Data curation, Methodology, Writing – original draft, Writing – review & editing. Kramer Daniel R.: Conceptualization, Data curation, Methodology, Writing – review & editing. Gilbert Zachary D.: Conceptualization, Data curation, Methodology, Writing – original draft, Writing – review & editing. Cavaleri Jonathon: Conceptualization, Data curation, Methodology, Writing – original draft, Writing – review & editing.

Files

1-s2.0-S0168010224000099-main.pdf

Files (3.7 MB)

Name	Size	Download all
1-s2.0-S0168010224000099-main.pdf md5:1e0efe5e943d5dd71dd8865521032a2d	3.7 MB	Preview Download

Additional details

	All versions	This version
Views	0	0
Downloads	0	0
Data volume	0 Bytes	0 Bytes